Lisa Parr -selected References
نویسنده
چکیده
1 Parr, L. A., Modi, M., Siebert, E., & Young, L. J. (2013). Intranasal oxytocin selectively attenuates rhesus monkeys' attention to negative facial expressions. Psychoneuroendocrinology, 38, 1748-1756. Notes: Intranasal oxytocin (IN-OT) modulates social perception and cognition in humans and could be an effective pharmacotherapy for treating social impairments associated with neuropsychiatric disorders, like autism. However, it is unknown how IN-OT modulates social cognition, its effect after repeated use, or its impact on the developing brain. Animal models are urgently needed. This study examined the effect of IN-OT on social perception in monkeys using tasks that reveal some of the social impairments seen in autism. Six rhesus macaques (Macaca mulatta, 4 males) received a 48 IU dose of OT or saline placebo using a pediatric nebulizer. An hour later, they performed a computerized task (the dot-probe task) to measure their attentional bias to social, emotional, and nonsocial images. Results showed that IN-OT significantly reduced monkeys' attention to negative facial expressions, but not neutral faces or clip art images and, additionally, showed a trend to enhance monkeys' attention to direct vs. averted gaze faces. This study is the first to demonstrate an effect of IN-OT on social perception in monkeys, IN-OT selectively reduced monkey's attention to negative facial expressions, but not neutral social or nonsocial images. These findings complement several reports in humans showing that IN-OT reduces the aversive quality of social images suggesting that, like humans, monkey social perception is mediated by the oxytocinergic system. Importantly, these results in monkeys suggest that IN-OT does not dampen the emotional salience of social stimuli, but rather acts to affect the evaluation of emotional images during the early stages of information processing
منابع مشابه
Familiar and unfamiliar face recognition in crested macaques ( Macaca nigra ) JérômeMicheletta 1 , Jamie Whitehouse 1 , Lisa A . Parr 2 , 3 ,
JérômeMicheletta1, Jamie Whitehouse1, Lisa A. Parr2,3, Paul Marshman1, Antje Engelhardt4,5 and Bridget M. Waller1 1Centre for Comparative and Evolutionary Psychology, Department of Psychology, University of Portsmouth, Portsmouth, UK 2Center for Translational Social Neuroscience, Silvio O. Conte Center for Oxytocin and Social Cognition, Department of Psychiatry and Behavioral Sciences, and 3Yer...
متن کاملFamiliar and unfamiliar face recognition in crested macaques ( Macaca nigra ) JérômeMicheletta 1 , Jamie Whitehouse 1 , Lisa A . Parr 2 , 3 , Paul Marshman 1 , Antje Engelhardt 4 , 5 and
JérômeMicheletta1, Jamie Whitehouse1, Lisa A. Parr2,3, Paul Marshman1, Antje Engelhardt4,5 and Bridget M. Waller1 1Centre for Comparative and Evolutionary Psychology, Department of Psychology, University of Portsmouth, Portsmouth, UK 2Center for Translational Social Neuroscience, Silvio O. Conte Center for Oxytocin and Social Cognition, Department of Psychiatry and Behavioral Sciences, and 3Yer...
متن کاملتعیین ویژگی‌های اجتماعی، اقتصادی و زراعی گندم‌کاران شهرستان‌های اهواز، دزفول وبهبهان با توجه به پذیرش روش‌های کشاورزی پایدار کم نهاده (LISA )
The main objective of this article is to present the results of a study done about the social, economical, and farming characteristics of wheat farmers in Khuzestan province of Iran regarding adoption of low input sustainable agriculture (LISA). LISA practices have tended to reduce the use of fertilizer pesticides, and maximal tillage, but, rely more on crop rotation, crop residues, animal manu...
متن کاملتعیین ویژگی‌های اجتماعی، اقتصادی و زراعی گندم‌کاران شهرستان‌های اهواز، دزفول وبهبهان با توجه به پذیرش روش‌های کشاورزی پایدار کم نهاده (LISA )
The main objective of this article is to present the results of a study done about the social, economical, and farming characteristics of wheat farmers in Khuzestan province of Iran regarding adoption of low input sustainable agriculture (LISA). LISA practices have tended to reduce the use of fertilizer pesticides, and maximal tillage, but, rely more on crop rotation, crop residues, animal manu...
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